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Gastroretentive Drug Delivery systems of Baclofen
79,10 € *
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Over the past three decades, the pursuit and exploration of devices designed to be retained in the upper part of the gastrointestinal (GI) tract has advanced consistently in terms of technology and diversity, encompassing a variety of systems and devices such as floating systems, raft systems, expanding systems, swelling systems, bioadhesive systems and low-density systems. Gastric retention will provide advantages such as the delivery of drugs with narrow absorption windows in the small intestinal region.This book consists of detail aspect of gastroretentive drug delivery systems. Authors had design and developed various gastroretentive formulations of narrow absorption window drug baclofen.

Anbieter: Dodax AT
Stand: 18.01.2020
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Don't Look Now
8,41 € *
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'Now, ill-lit, almost in darkness, the windows of the houses shuttered, the water dank, the scene appeared altogether different, neglected, poor, and the long narrow boots moored to the slippery steps of cellar entrances looked like coffins.'A slow-burning masterpiece of horror recounting a grieving couple's fateful visit to Venice, Don't Look Now is accompanied here by further short tales of desire and dread.Ten new titles in the colourful, small-format, portable new Pocket Penguins series

Anbieter: Dodax AT
Stand: 18.01.2020
Zum Angebot
Don't Look Now
8,41 € *
ggf. zzgl. Versand

'Now, ill-lit, almost in darkness, the windows of the houses shuttered, the water dank, the scene appeared altogether different, neglected, poor, and the long narrow boots moored to the slippery steps of cellar entrances looked like coffins.'A slow-burning masterpiece of horror recounting a grieving couple's fateful visit to Venice, Don't Look Now is accompanied here by further short tales of desire and dread.Ten new titles in the colourful, small-format, portable new Pocket Penguins series

Anbieter: Dodax
Stand: 18.01.2020
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Novel Gastroretentive Dosage Forms
59,00 € *
ggf. zzgl. Versand

A gastroretentive dosage form (GRDF) is retained in the stomach for an extended time period. Such a dosage form would slowly release narrow absorption window drugs absorbed predominantly in the stomach and small intestine, to their absorption sites. This should enhance bioavailability and reduce adverse effects. Thus, the general objective of this research is to broaden the therapeutic potential of narrow absorption window drugs using novel GRDFs. The outcomes of this work suggest that gastroretentivity of dosage forms can be efficiently prolonged by a combination of extending the dosage form s physical dimensions with the incorporation of rigid constituents. The combination of prolonged gastroretentivity and controlled release kinetics significantly extended the time periods during which the concentrations of model drugs in the blood were considered therapeutic. In addition, this study is the first to demonstrate the ability to enhance the pharmacologic effects of a drug (furosemide) in humans, using a GRDF. This work illustrates the prospective clinical benefits of novel GRDFs used with drugs that have narrow absorption windows.

Anbieter: Dodax
Stand: 18.01.2020
Zum Angebot
Novel Gastroretentive Dosage Forms
60,70 € *
ggf. zzgl. Versand

A gastroretentive dosage form (GRDF) is retained in the stomach for an extended time period. Such a dosage form would slowly release narrow absorption window drugs absorbed predominantly in the stomach and small intestine, to their absorption sites. This should enhance bioavailability and reduce adverse effects. Thus, the general objective of this research is to broaden the therapeutic potential of narrow absorption window drugs using novel GRDFs. The outcomes of this work suggest that gastroretentivity of dosage forms can be efficiently prolonged by a combination of extending the dosage form s physical dimensions with the incorporation of rigid constituents. The combination of prolonged gastroretentivity and controlled release kinetics significantly extended the time periods during which the concentrations of model drugs in the blood were considered therapeutic. In addition, this study is the first to demonstrate the ability to enhance the pharmacologic effects of a drug (furosemide) in humans, using a GRDF. This work illustrates the prospective clinical benefits of novel GRDFs used with drugs that have narrow absorption windows.

Anbieter: Dodax AT
Stand: 18.01.2020
Zum Angebot